In the presence of PSA and other factors affecting the IGF-I/IGFBP-2 and IGFBP-5 binding, it will result in the delivery of the IGFs to the IGF-1R and activation of the downstream signalling 21 pathway, thus helping the progression to castration resistant disease [ 152, 153].
Future studies in larger patient populations will help determine whether exosomes, and their microRNA and/or protein cargo, can help diagnosing the progression of uveal melanoma.
Proponents of renewable energy argue that an alternative approach will allow for more sustainable energy usage, help support future growth, avoid price spikes, allow for energy independence, and ultimately help slow the progression of global warming.
We speculate that this will facilitate future longitudinal noninvasive assessments of new therapies to help slow the progression of OA.
Additional application of biochemical markers, which are able to sensitively detect ongoing joint damage, may facilitate the appropriate use of targeted therapy in RA and help reduce the progression of joint damage in these patients.
"The M.S. Society has shown that this drug will help slow the progression of my disease.
Finite element analysis was used to help understand the progression of fatigue damage and the effect of stress concentration features.
Early detection of decreased kidney function can help prevent the progression of kidney disease to kidney failure and cardiovascular events.
Low-protein diets can help slow the progression of kidney disease, but they can make the muscle wasting that the disease causes even worse.
MRI measurements of the relaxation time T2 can help estimate the progression of diseases such as osteoarthritis and its associated tissue deterioration.
