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The level of variation observed among these structures is progressively higher towards the cytoplasmic end of the helix (up in Fig. 4A and right in Fig. 4B).
The very tip of the C-terminal α-helix that touches the bottom sleeve is essential for rapid catalysis and generation of full torque, but the rest of the C-terminal helix up to the base of the axle is completely unnecessary for the residual rotation with half the torque.
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The fic domain core includes eight α-helices, arranged as a six-helix up and down bundle (a1 - a5 and a') decorated by two additional helices (a6 and a7) lying almost perpendicular to the bundle.
The C-terminal domains are primarily composed of α-helices and form a four-helix up and down bundle.
For a wide range of concentrations of both surfactants (oxyC4 and oxyC8), the protein does not exhibit any visible change of the content of α-helixes, up to about 1.2 mM, and is equal to approximately 38%%.
The 4-helix up-down, left-handed twist bundle is a common fold (SCOP 47161), and it forms the core of this and other domains in the talin rod.
The 4-helix up-down-up-down fold results in the N- and C-termini of the domain being at the same end of the bundle (Fig. 3A), whereas with a fifth helix the N- and C-termini are at opposite ends of the bundle.
Depending on the experimental conditions, oxygen concentration in the helix was up to twice that of the horizontal tube.
Mark Proegler, a BP spokesman, said preparations continued for hooking a third vessel, the Helix Producer, up to the systems, which would increase the capture capacity from 28,000 barrels a day to 53,000 barrels.
Shares of Helix are up over 9%.
Shares of Helix are up 12%.
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