Sentence examples for helix towards from inspiring English sources

To the best of our knowledge, the observation that the conformational change of one specific helix towards the loop correlates with the loss of the di-iron cluster is the first case described for this superfamily.

For instance, the shift of the N-terminal part of the α2 helix towards the α3 helix closes the gap between the two, where α1 helix moves outwards.

This helical configuration of the metal binding motif leads to the presentation of the invariant acidic residues in the consensus sequence (D491, E497 and E502) on the same side of the helix towards the surface of the protein.

This contraction may represent the molecular switch that activates transmembrane signaling in the receptor, causing a piston-like movement of the second transmembrane helix towards the periplasm.

The surface of this α8 helix towards the cytoplasm is mainly hydrophobic, which suggests that this helix might interact with other components in the cytoplasm (Supplementary information, Figure S7).

While the combination of structural observations and mutagenesis data clearly highlights the functional contribution of the C-terminal portion of the Bridge Helix towards controlling the rate of the NAC, the role of the N-terminal portion of the Bridge Helix has thus far remained enigmatic.

First, binding of TPX2 causes a slight rotation of the αC-helix towards the catalytic center, thus allowing for the conserved, stabilizing E181-K162 ion pair to form.

This can either be due to a shift of α helix absorption towards higher wavenumbers or to the co-existence of two types of α helical structure.

However, in very few pMHC-I cases, such as 1mwa (PDB code), the MHC helices exhibit a ring of mostly positive residues with one/two negative residues on either helix contributing towards TR docking (Figure 2c).

Three different alternative alignments were considered: the first is to shift the helix insertions towards the C-terminus.

With pleiotropic mechanisms of action, it binds to the DNA minor groove, causing double helix bending towards the major groove, modulating inflammatory responses in the tumor microenvironment, and promoting tumor cell differentiation [ 28].