Sentence examples for helix binding from inspiring English sources

That's because "transcription factors" and other regulatory elements - proteins made by this controlling DNA - hopscotch across each cell's double helix, binding to it in a way that turns genes on and off or up and down like a toddler who has just discovered light switches and dimmer dials.

The classical Early Growth Factor (EGR) gene, zif268 (Fig. 1) shows the main recognition motif, a helix binding to the major groove of the DNA.

However, because the SNARE helix binding back to the longin domain would occur at the same site as Hrb binding, they would be mutually exclusive.

The location and charged nature of the new surface created by linker helix binding abrogates the ability of RING1 to form canonical interactions with a Ub-charged E2.

The solid lines represent the predicted binding thermogram assuming that both scCPX and truncated SNAREΔ60 are bivalent with well-defined independent thermodynamic parameters describing CPX central helix and CPX accessory helix binding (B ).

As expected, addition of Cpx(26-83) yielded onlyieldedll amonly of heat that again ismall namount extensiof of theatirecthattragain of the central helis binding sithe

Slowing the photocycle with a targeted mutation may lead to photocontrol of K-helix binding by a monomeric form of the protein.

Our original expectation was that the enhanced flexibility of the light state of PYP would then permit the E-helix to adopt a conformation competent for K-helix binding.

ID2 (inhibitor of DNA binding 2, dominant negative helix-loop-helix binding protein), which was found to be pro-apoptotic in osteosarcoma cells [ 80], was exclusively induced in parental cells.

To visualize K-helix binding directly, we synthesized a fluorescein-labeled K-helix peptide [K-helix-F; Ac-CAAA IAALKEK 2IAALKGW-NH2]. Ac-CAAA IAALKEK 2IAALKGW-NH2]–K-helix-F complexes analyzed by native PAGE.

This analysis was extended (Table 2) by superimposing structures of other α-helix binding EF-hand pairs onto lobe 2 of HsAPC-1 RD independently of the bound α-helix.