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We hypothesised that these epithelial cells are shed from the ductal and luminal epithelial layers through either a heightened turnover of the secretory tissue, or as a consequence of the mechanical shear forces associated with the continued filling and emptying cycle associated with breast milk synthesis and lactation.
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This presumption is based on findings that oxidative stress augments telomere attrition per replication (31– 34) and the inflammation heightens the turnover of leukocytes, which would further increase LTL shortening with age.
It will be important to determine whether the degree of this influence increases during times of heightened bone turnover (e.g., pregnancy and lactation).
Inflammatory processes cause heightened leukocyte turnover rate that can result in a greater loss of leukocyte telomere repeats over time [ 2, 4, 33].
In addition, at least two other Jurassic intervals show heightened faunal turnover affecting mainly marine invertebrates one in Early Jurassic time and another at the end of the period.
After a 14-day alcohol holiday, the women's blood contained heightened levels of a molecule that gets released during bone turnover.
The succinate that accumulates when SDH complex activity is impaired leads to reduced turnover of hypoxia-induced factor 1 alpha (HIF1Α) and heightened expression of HIF1A target genes including vascular endothelial growth factor [ 21].
"Dianetics" also promises heightened powers of intelligence and perception.
Cold war politics, which heightened suspicion of foreigners, complicated matters.
It cited heightened risks of the country's growth prospects.
Heightened awareness of division can make communities impossible to rule.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com