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But the F.D.A. from the start required a black-box warning about a heightened risk of bleeding with Effient, a risk that was highlighted by many physicians interviewed for this article.
This limits its use because physicians can be reluctant to prescribe warfarin to the elderly or patients at heightened risk of bleeding, such as those with a history of falls, and intracranial or gastrointestinal hemorrhage [ 61].
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Giant aneurysms are managed with combined anticoagulation and antiplatelet therapies, heightening risk of bleeding complications.
Clinical trials using glucocorticoids in patients with acute alcoholic hepatitis showed minor benefits but ultimately were terminated because of a heightened risk of sepsis and gastrointestinal bleeding (Maddrey et al. 1978).
New York, NY (May 25 , 2017—Women with preeclampsia, a common complication of pregnancy, face a heightened risk of stroke during pregnancy and postpartum if they have urinary tract infections, chronic high blood pressure, or clotting or bleeding disorders, according to a study by Columbia University Medical Center (CUMC) and NewYork-Presbyterian researchers.
The child thus faces a heightened risk of sexual assault.
Such people face a heightened risk of developing new polyps.
Patients with active cancer have a heightened risk of venous thromboembolism (VTE).
Hypertrophic cardiomyopathy (HCM) is characterized by ventricular hypertrophy and heightened risk of premature sudden cardiac death.
Immunization is key to protecting term and preterm infants from a heightened risk of infection.
And people with depression face a heightened risk of heart disease.
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