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The markers tested included oxidized and reduced glutathione and cysteine, and again a pattern was clear: galactose and paraquat synergized to create heightened markers of oxidative stress in both mutant and control animals.
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Markers outside inverted regions, but near the breakpoints, tend to have heightened divergence, similar to markers found within inversions (Machado et al. 2007; Noor et al. 2007; Kulathinal et al. 2009).
A difference between UP and BD might be anticipated for R2 and YMRS scores, as we would not anticipate high levels of manic-like symptoms in the UP group and also, previous publications suggest that there is heightened variability in circadian markers across mood phases in BD (Novakova et al. 2015).
For this reason, there is heightened interest in early markers of retinopathy to be used as surrogates to test adjunct therapies.
Syphilis provides an informative marker of heightened HIV risk and may be an important consideration in assessing the need for PrEP.
Overweight/obese adolescents with HbA1c in the at-risk/prediabetes category demonstrate impaired β-cell function relative to insulin sensitivity, a metabolic marker for heightened risk of type 2 diabetes.
On clinical grounds, bvFTD and SD were predicted to have the most marked derangements of emotional salience processing, yet patients with AD here showed abnormal affective coding of sounds: this may constitute a marker of heightened behavioral sensitivity to emotional stimuli underpinned by relative enhancement of salience network activity, recently proposed as a hallmark of AD [8], [14].
Although controversy is likely to continue surrounding the adoption of HbA1c-based criteria for the diagnosis of prediabetes and diabetes in youth, these data support that the ADA HbA1c criteria for prediabetes correspond to impaired β-cell function in overweight/obese youth, a metabolic marker of heightened type 2 diabetes risk.
This movie's eerie mood was heightened by the BIGGEST reel marker I've ever seen: it was a gigantic, scrawled 14 or perhaps E14 that covered the entire middle of the film.
HD patients with diabetes demonstrated no differences in the level of biologic markers for accelerated hemostasis, heightened inflammatory response or pathologic degrees of oxidative stress.
In a prior study of diabetic and non-diabetic individuals on RRT, we evaluated relationships between prior cardiovascular events (PCVE) and plasma markers for accelerated hemostasis, heightened inflammatory response as well as pathologic degrees of oxidative stress [ 1].
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