Recently, the clinical relevance of the EGFR has been heightened in light of the development of the EGFR tyrosine kinase inhibitors, Getifinib and Erlotinib and EGFR monoclonal antibodies Cetuximab that have been demonstrated to have antitumour activity in solid tumours including non-small cell lung cancer (NSCLC) (Giaccone et al, 2004; Herbst et al, 2004a, 2004b; Lynch et al, 2004b).
Larry's photographs possess a quality of hard-edged California light, heightened color, optical precision, and, often, domestic familiarity made more fascinating by the power of his imagination.
Ms. Geesaman's lush photographs of parks and gardens in Europe and the United States combine exacting formal order, heightened color, melting light and shifty focus.
Rendering the charade à la Velázquez — only more so, with heightened contrasts of light and dark and stabbing local colors — produced a surplus of visual delight that practically overwhelmed the frivolous subject.
In the coda of her Act II solo she suddenly added a soft out-of-the-blue triple pirouette that had the audience gasping aloud not because of its virtuosity but because of its unexpected rightness: it heightened Odette's light.
An abstract video by the director Habib Azar added little, but suggestive lighting heightened dramatic effect.
Its mysterious radiance verges on the sublime, a sensation heightened by elegant lighting design from Ji-Youn Chang.
Inspired by classical madonna-and-child imagery, Asselin used heightened and dramatic lighting to call attention to the intimate gestures of her subjects.
Such carnal physicality and charged emotion, heightened by chiaroscuro lighting delineating figures that emerge from darkness, came to define Caravaggio's oeuvre.
Jacopo Robusti, called Tintoretto, was most interested in Titian's use of dramatic light and heightened emotion.
