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Elevated pTH activity in ZI does not simply reflect underlying differences in enzyme expression and instead, might be due to neglectful mice having a heightened input to ZI.
Besides direct stimulation, another likely source of such heightened input is the spontaneous activity that typically develops in neuropathic pain states (Kajander and Bennett, 1992; Liu et al., 2000).
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This finding is consistent with previous reports demonstrating that activity in the visual cortex is particularly robust during the presentation of emotionally arousing visual stimuli, perhaps due to re-entrant enhancement of V2 activity being driven by motivational processes that heighten input from the amygdala.
We propose a model in which heightened afferent input associated with electrical muscle stimulation plays a key role in neural adaptations to EST (Fig. 1).
During central sensitization, intensely heightened peripheral input decreases thresholds necessary to elicit action potentials in dorsal horn neurons.
Various categories of treatment are available, including behavioural procedures such as changes in head postures, heightening sensory input prior to the swallow, voluntary manoeuvres, exercise programmes, medications and surgical procedures.
Concentrations of lipids are highest in goethite layers which represent environments of heightened aqueous activity conducive to habitation, and hence predisposed to receiving heightened microbial fossil inputs.
All these things allow you to understand the Zen of the racetrack and open yourself up to the sensory input and heightened awareness that high-performance driving demands.
One hypothesized risk factor for anxiety is heightened responses to sensory input.
Brain scans (FMRI) illustrated that participants' visual cortex responsiveness was heightened to auditory and tactile sensory input after only five days of blindfolding for over an hour each time.
You need lots and lots of time to steer any car in snow, and a tall SUV needs still gentler inputs because of that heightened rollover risk.
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