Enhanced safety and heightened efficacy have been achieved for a wide range of drug classes, including antitumor agents, antivirals, antifungals, antimicrobials, vaccines, and gene therapeutics.
In addition, Abraxane exhibits linear pharmacokinetics and can therefore be given at a relatively higher dose than standard intravenous paclitaxel, leading to a higher therapeutic ratio and heightened efficacy in solid tumours, mainly metastatic breast cancer [ 146, 147].
Expanding on previous studies, our findings identify a number of factors correlated to full remission from depression: such as greater psychosocial functioning, more-positive beliefs regarding antidepressant medication, heightened self-efficacy in managing/preventing depression, and lowered neuroticism.
In sum, our engagement-behavior data and scientific writing data suggest that immediate dissemination of student results to a popular community resource can heighten the efficacy of course-based research by motivating student engagement with all aspects of the scientific process, including critical evaluation of their own data and that of others.
Along with efficacy, heightened awareness surrounding safety of new therapeutic approaches is essential.
Although this question was previously overlooked because of the restricted geographic distribution of many etiologic agents of VHF for which VSV-based vaccines have been tested, the emergence of EBOV in countries in West Africa to which LASV is endemic has heightened concerns of use and efficacy of 1 vaccine platform against multiple agents of VHF (8 ).
For example, engagement can lead to increases in self-efficacy, heightening both awareness and a sense of relevance, while a sense of self-efficacy fostered by success can encourage further exploration of the subject matter, underscoring the relevance of the material to the student's life and promoting greater engagement.
Ongoing successes in a specific domain of functioning, in this case, may heighten personal self-efficacy beliefs (Britner & Pajares, 2006; Lent, Lopez, & Bieschke, 1991; Liem, Lau, & Nie, 2008; Phan, 2012c) and inform learners of their capabilities.
At an individual level, empowerment is a process by which individuals experience heightened feelings of control and self-efficacy [ 8- 13].
There is little known about associations between self-efficacy and subjective oral health among populations at heightened risk of dental disease.
In addition to heightened innate immune responses, the addition of multiple innate receptor agonists in vaccine formulations can enhance the efficacy of pathogen or cancer cell specific humoral and cellular immune responses [10].
