The phenomenon of 'genetic anticipation' is a hallmark of the (CTG n CAG n TNR instability disorders, in which an increase in the number of microsatellite repeats is correlated with an earlier age of onset and heightened severity of the disease in successive generations.
And when she closes her eyes at night, she's living in gray-blue Manhattan as Marty, a literary agent with her hair pulled back to heighten the severity of her loveless life in the big city.
In a second phase, the researchers found that the participants who were more resistant to cortisol also produced more cytokines, components of the immune system that promote inflammation and heighten the severity of symptoms.
The city says such measures would help protect against the long-term effects of climate change, which by raising sea levels will not only alter the shape of the shoreline but also heighten the severity of flooding from even minor storms.
This kind of disaster risks is expected to increase in the future due to climate change, whose impacts are likely to heighten the severity and occurrence of extreme HM events, such as droughts and floods (Stern 2007, p. 76; IPCC 2007, 2012).
However, the odd angle of the challenge, the speed of the tackle and the clumsy nature of it all caused Davis to twist and fall awkwardly, heightening the severity of the contact.
But don't leave it open-ended, because worry compounds itself, magnifies the fear and heightens the severity of the crisis.
While these data are supportive of the dose-response hypothesis, the molecular underpinnings of this heightened disease severity on myocyte function remain largely unanswered.
This heightened disease severity was not due to an inability to control viral replication as there was no difference in the viral titer in the heart at the peak of infection.
Hospitalizations involving inter-hospital transfer deserve further investigation given this finding which corroborates prior reports which have described an association between interhospital transfer and both heightened illness severity and elevated hospital resource use [ 12- 14].
