Sentence examples for height variants from inspiring English sources

The current evidence suggests that some height variants may indeed be pleiotropic or in LD (i.e. co-inherited) with other variants.

Good examples come from the 'Cavendish' group of dessert bananas, where there are several height variants such as (in approximate descending order) 'Lacatan', 'Robusta', 'Valery', 'Giant Cavendish', 'Grand Naine'Dwarfarf Cavendish', 'Petit Naine' and 'Dwarf Parfitt', and other variants, such as 'Williams' and 'Zelig'.

In order to explore the connection between known height-associated SNPs and teeth phenotypes more deeply, we took 180 robustly associated height variants from the Lango Allen et al. (12) Giant Consortium meta-analysis and examined the degree to which these SNPs were associated with tooth eruption (Supplementary Material, Table S5).

Many recent publications using genome-wide association scans have highlighted that the genetic variants which underpin height variation as well many other complex traits are likely to have very small effect sizes [23] [25].

Indeed, genome-wide association study (GWAS) have revealed hundreds of variants that contribute to the variability of height but could explain only a limited part of it, and no single variant accounts for more than 0.3% of height variance.

No single variant identified in these GWAS explained more than 0.3% of height variance.

The combined effect of all 20 genetic variants associated with adult height in a recent study explained only 3% of height variation [ 10].

We highlight specific findings, including a variant in the promoter of the miRNA let-7 that may contribute to human height variation.

Looking at the relevant SSc tissues, fibroblasts were the most enriched with enhancer marks for height-associated variants, and vascular tissue was enriched with aortic root size variants.

Our results suggest that BMP4 is likely to contain novel height-associated variants and could also be followed up in this context.

A weighted allelic score of height-associated variants was not strongly related to tooth eruption and there seemed to be little consistency in the direction of allelic effects for 180 height-associated SNPs across height and tooth eruption phenotypes.