Factors explaining pubertal growth in response to GH therapy: gender, age, the difference between the child's height standard deviation score (SDS) and midparental heightSDS (diffH-MPH) at the onset of puberty, and GH dose were identified from the KIGS observational study, but the IGF-I variable was not available in that study [ 14].
Compared to healthy Dutch children, mean height standard deviation score values for male and female EvC patients were −3.1 and −3.0, respectively.
Study design Twelve short (height standard deviation score, −3.2 ± 0.1) non GH-deficient childrenon GH-deficientgirls) were studied at 9.3 ± 1.0 years of age.
To investigate in an open-label randomized study, the effect of two doses of growth hormone (GH) on final height and height velocity during the first 2 years of treatment of children with idiopathic short stature (mean baseline height standard deviation score [SDS] −3.2).
HSDS = height standard deviation score; THSDS = target height standard deviation score Table 4 shows how many children in the correctly referred group complied with the 7 different referral criteria mentioned in the DCG (although longitudinal data were used for the analyses a child could only meet a specific referral criterion once).
To estimate the effect of catch-up growth, the SGA children were reclassified into two additional subgroups according to their corrected height standard deviation scores (SDSs): actual height SDS − midparental height SDS, where midparental height for boys equals father's height + (mother's height + 13)/2 and for girls equals mother's height + (father's height − 13)/2 (9, 10).
Results: Mean adult height standard deviation score — midparental height standard deviation score was −1.1 for both sexes.
Linear growth measured by median height standard deviation score improved from -0.7 before transplantation to -0.2 after transplantation.
Auxological parameters [including height, height velocity, and their associated height standard deviation scores (HSDS)] were obtained from 39 patients.
Objective: To assess the relationship between insulin-like growth factor-1 (IGF-1), the growth hormone (GH) dose utilized to treat GH-deficient children and the changes noticed in height-standard deviation score (H-SDS) and height velocity (HV).
> -wrap-foot>> -wrap-foot> DBH, diameter at breast height; TH, total height; H, stem height; SD, standard deviation; CV, coefficient of variation; SE, standard error.
