The parameter and weight adjustment of both methods appeared heavy time-consuming and have not succeed any experiment.
In other words, to obtain an honorable yield, one needs to use several docking programs and rescore all the poses gathered in one pool, which represents a heavy, time-consuming procedure.
Sound too time consuming?
He reports he is working currently in a movie called "Planet of the Frog Men," which requires heavy amphibian makeup, extremely time consuming in its application and removal.
MRC researchers, meanwhile, continued to feel the reforms as a heavy administrative burden, compounded by time consuming obligations to act as expert advisers to the government [ 14, 15].
However, thermoplastic splints can be time consuming to fabricate, heavy, uncomfortable and difficult to don by patients and family.
From a clinical perspective, TEM-based methods are impractical, as they are time consuming, costly, and rely on heavy processing of the sample.
Counselling patients about insulin initiation was seen as time consuming especially in government clinics with heavy patient load.
However, there is often heavy clinical demand for current scanning equipment and imaging can be time consuming.
It can be time consuming to deploy, the sand/gravel component makes it heavy and/or costly to transport, or reliant on local materials for the media.
