Establishing a clear physical chemistry basis for interpreting protein hydrogen exchange provides a means to characterize both the structure and the population of the protein heavy-atom reorganization processes that facilitate solvent access for the structurally buried amides.
For such slow carbon acids, the charge delocalization that provides resonance stabilization of the anion progresses more slowly than does proton transfer (68), and heavy-atom intramolecular reorganization is generally the rate-limiting process (69).
It is equally certain that workers, retirees, suppliers, and the economy at large will pay heavy costs for those reorganizations.
As all who have been involved in AIDS know, despite the successes, AIDS needs a radical reorganization; it is top heavy-- too mucheavy-- toostudies, reports, conferences and techeavy-- toostance," in the sumuchy of Bill Clinton.
Saxon Riley, who led Lloyd's of London through a sweeping reorganization and helped it survive heavy losses in the World Trade Center attack in 2001, died on July 25.
The merger incurred heavy debt, and, after bankruptcy proceedings (1983) and reorganization, Continental reduced services by two-thirds.
With heavy lobbying, insurers quietly obtained legislative permission for such reorganizations in the late 1990's in about 25 states.
Thlaspi caerulescens, which is a well-studied heavy metal accumulator, was moved to the genus Noccaea during this reorganization.
Houlihan's Restaurants Inc., which had filed for Chapter 11 bankruptcy protection because of heavy competition in the casual-dining industry, won court approval for its reorganization plan.
There was heavy gestural humor in Mr. Watts's "Vodville" and the band's japing reorganization of Thelonious Monk's "Rhythm-a-Ning"; and heavy pathos in the ballads "Hope" and "Fate," as well as the cathartic bass solo "And Then He Was Gone".
