Sentence examples for heavy chain involved from inspiring English sources

We expressed C-terminal fragments of human clathrin heavy chain involved in trimerization ("hub" fragments) recombinantly in E. coli [40], [41].

By bioinformatics analysis, we identified that MYH9, which encodes a myosin IIA heavy chain involved in the promotion of cancer cell migration or invasion, as a putative let-7f target.

Additional studies have identified other regions of interaction, including the proteolytic target residues and the surrounding regions, in the FVa heavy chain involved in the enzymesubstrate complex formation [ 26- 28].

A more rigorous test to verify which cleavage in prothrombin is affected by the deletion at the COOH terminus of factor Va heavy chain involves the study of the activation of a prothrombin molecule that cannot be cleaved at Arg such as rMZ-II (41).

Surprisingly, Sox6 protein levels were not diminished in transgenic mice, however the myosin heavy chain classically involved in hypertrophy, ß-myosin heavy chain (ß-MyHC), was markedly increased (Fig. 4B).

The COOH-terminal region of factor Va heavy chain is involved in the interaction with prothrombin (18, 19).

Overall, the data demonstrate that amino acid region 659−663 of factor Va heavy chain is involved in the activation of prothrombin by factor Xa.

We have also established that residues DYDY from the COOH terminus of factor Va heavy chain are involved in cofactor function and regulate the rate of meizothrombin cleavage by prothrombinase at Arg.

Heavy chain rearrangements involve an additional gene segment (DH) and two junctions rather than the one that light chain rearrangements have.

For functional analysis in depth, we found that two significantly increased proteins, disabled homolog 2 (Dab2) and clathrin heavy chain (CLTC), were involved in VEGF receptor endocytosis, serving as a mechanism to induce intracellular receptor signaling upon the stimulation of VEGF signal, which is referred as a regulator leading to angiogenesis13.

The data support the contention that the lymphoma in this form of alpha heavy chain disease may involve B lymphocytes but that the abnormal protein may be produced by other cells.