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The first network module is heavily enriched for cell death and apoptosis and also shows enrichments for cell differentiation, cellular development processes, and system and multicellular organismal development, as well as cancer pathways.
The uORFs observed are highly discrete, specific, and heavily enriched in meiosis relative to any other condition examined to date, but the molecular basis for these unusual observations remains a mystery.
At least the top 10 nm of the SnLi samples were heavily enriched with Li, and Sn/Li ratios varied in the range 0.8 5% depending on eutectic treatment conditions.
A simple definition of penetrance is used that is often applied in medical genetics—namely, the proportion of observed mutation carriers that are affected to provide a metric that would be useful to clinical geneticists in a setting in which disease is heavily enriched, for example, in diagnosing children with developmental delay.
SCNAs in TGF-β pathway genes were heavily enriched in Group 3 (P = 5.37 × 10−5, Fisher's exact test) and found in at least 20.2% of cases, indicating that TGF-β signalling represents the first rational target for this poor prognosis subgroup (Fig. 3d).
These deposits are clearly discontinuous in nature and are usually heavily enriched in Mn relative to Fe (Fig. 13).
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Mr. Esber gave his collaborators plenty to work with in the form of a bluntly drawn, heavily lined image enriched by historical details.
One example of the SCBC method for single-cell chip-based proteomic investigation first heavily dilutes a FACS enriched population before loading them into microchambers.
The 16S rRNA gene data indicated that the most heavily oil-impacted sediments were enriched in an uncultured Gammaproteobacterium and a Colwellia species, both of which were highly similar to sequences in the DWH deep-sea hydrocarbon plume.
The set of heavily mutated proteins was significantly enriched in c-type cytochromes and in membrane-bound transport proteins (Table 3, Additional file 1: Table S6).
Module 7 is the largest network module and is enriched in proteins heavily implicated in diverse processes, such as cell adhesion (P = 2.7E-18), anatomical structure development (P = 9.8E-09) and coagulation (P = 2.4E-07).
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