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Its biggest problem in the heavily computational loading would obviously restrict the related uses in real-time cases.
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"We rely very heavily on computational methods, computational design, and we do some great imagery.
He notes that climate modeling, which depends heavily on computational physics, must compete with other fields for a dwindling supply of physics graduates.
The development of such devices relies heavily upon computational models, from the pre-conceptual stages through detailed design, licensing, and operation.
We must therefore, for now, rely heavily on computational methods to predict TFBSs.
Research using multiparametric imaging data relies heavily on computational approaches for image acquisition, data management, visualization, and correct data interpretation [ 110- 112].
Unfortunately, the algorithm itself and the double loop of nested cross-validation procedures heavily demand computational power, in contrast to more standard techniques, such as t-test, that are easier to run even by non-specialists.
In terms of the study of the role of miRNAs both methods when used in isolation rely heavily on computational methods to predict miRNA interaction and prioritise potential direct targets.
This related not only to the reluctance of toxicologists and regulators to educate themselves about new toxicologic methods but also the reluctance of scientists to rely more heavily on computational analyses of complex patterns of responses that cannot easily be understood in terms of known mechanisms and pathways.
This endeavor relies heavily on computational modeling, and while many approaches have been described, most were field tested prior to systematic analysis of TF sequence specificities by PBMs and MITOMI, before the importance of the intrinsic sequence preferences of nucleosomes was widely appreciated and before the use of tiling arrays and ChIP-seq became prevalent.
The target-based identification and optimization of new drug leads heavily relies on computational techniques.
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