The heat sensitizing effect of PEF treatments in the presence of 2% triethyl citrate on the Salmonella population could enable LWE producers to reduce the temperature or processing time of thermal treatments (current standards are 60 °C for 3.5 min in the United States), increasing the level of Salmonella inactivation and retaining the quality of non-treated LWE.
Thirteen dogs were entered into a pilot study to assess the toxicities associated with polyamine biosynthetic enzyme inhibitors as heat sensitizing drugs and whole body hyperthermia either alone or in combination.
In conclusion, the mechanism by which heat sensitizes cells for cDDP action seems to be the sum of multiple factors, which comprise heat effects on accumulation, adduct formation and adduct processing.
It has been shown that SCF c-Kit SCF c-Kit isignalingry to maistainecessarytor heat sensitivity, and that SCF can, like NGF, sensitize Iheat and produce rapid but short-lasting heat hyperalgesia in a TRPV1-dependent maintainMilenociceptoral., 2007).
To determine if GR82334 could be effective in naked mole-rats after SP administration, we sensitized heat-evoked foot withdrawal responses with 100 µM SP and 40 minutes later applied 100 nM GR-82334.
Cells labelled with haematoporphyrin derivative and irradiated with red light were sensitized by heat, particularly when the cells were heated after the exposure to light.
In naive mice, exogenous TNFalpha evoked heat hyperalgesia in vivo and sensitized nociceptive nerve fibers to heat in vitro.
In accordance with international standards [ 18] the antigenicity of each new batch of PPD tuberculin, in many laboratories, is routinely measured in animals sensitized with heat killed M. bovis cells.
Each rabbit was effectively sensitized with heat-killed M. bovis and all converted their tuberculin skin tests to positive prior to infection similarly to previous work (Table 1) (18).
Furthermore, these cells were highly sensitized to heat-induced apoptosis as shown by an increased percentage of Annexin-V staining and DEVDase activity.
HEK cells expressing AChR clusters, MuSK or ARMD were sensitized with heat-inactivated sera (30 min at 56°C) from the above patients at 1 : 20 dilution for 30 min at 37°C and then washed briefly.
