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Right heart volume and pressure overload led to severe dilatation of the CS (arrow), IVC and hepatic veins (asterisks).
The large right heart volume may also limit left ventricular volume within the pericardial sack and exacerbate the right to left stroke volume mismatch (ventricular-ventricular interdependence).
The proposed tumor burden metric is the segmented soft tissue volume contained within a chest space region of interest, excluding an estimate of the heart volume.
That is, a larger heart volume would allow for multiple pairs of ring electrodes and, therefore, it would be electrically divided into several smaller volume segments stacked on top of each other.
Due to the size of a mouse heart, the catheter size is drastically limited and it allows only for two pairs of the ring electrodes, where the two inner electrodes (i.e. b and c) define one cylindrical segment (whose height is L) of the heart volume.
As previously reported by Constantinesco et al. [6], an appropriate scaling factor was applied on the reconstructed images in order to approach the human reference heart volume, and a 20-segment polar map was automatically derived with the QPS software (Cedar-Sinai Medical Center, Los Angeles, USA) with constraining limits being manually adjusted [13 15].
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Central pulse wave velocity and heart volumes were measured before and after an 8-week aerobic training intervention.
This pulmonary blood volume is a part of the GEDV, which also includes the right and left heart volumes in diastole.
Surprisingly, quantification of ischemic areas, normalized to total heart volumes, revealed no significant differences in areas at risk between δCKO and δBKO mice after I/R injury.
In addition, the preload index GEDV is more complex than the heart volumes in diastole, since it also contains the pulmonary blood volume, which may vary largely during mechanical ventilation and when pulmonary vascular compliance changes.
Decreased contractile function (reduced fractional shortening of the left ventricle) and morphological changes (increased heart volumes, left ventricular dilatation, and myocyte hypertrophy) are characteristic features of this model [ 21, 22].
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