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Moreover, mice with heart specific deletion of MST1/2 or YAP during embryonic development display defective heart development[75 77].
Heart specific expression of MCP-1 is sufficient to induce monocyte/macrophage migration to the heart leading to myocarditis and fibrosis [36].
Moreover, miR-1 is annotated as muscle and heart specific [ 91– 93] and induced by IFN-β [ 94].
Using double in situ hybridisation, Xfzd7 expression showed overlapping with that of early heart specific markers including XNkx2.5, XTroponin-1C, Gata4, Gata5 and Gata6.
In the animal study, DG post-treatment at the reperfusion phase promoted their function recovery and inhibited heart specific enzyme release from a damaged heart.
We compared our constructed kidney metabolic model with two other tissue-specific models obtained from previous work [ 6, 9], including heart specific model and liver specific model.
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Researchers recently proposed that circulating miR-208a (a heart-specific molecule) might be used as an indicator for early drug-induced cardiotoxicity and biomarker of myocardial injury [53].
Clinical data suggest an important role for genetic susceptibility and heart-specific autoimmunity in the pathogenesis of chronic myocarditis and postviral dilated cardiomyopathy.
The bigger question is whether these are in fact heart-specific stem cells, and if so, exactly how they promote regeneration of heart tissue.
He cautions that this is a small sample of patients, and it's not known how many others with atrial fibrillation harbor heart-specific gene defects.
Heart-specific-GFP transgenic line Tg (cmlc2::GFP) was used to monitor the cardiac morphology in zebrafish embryos.
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