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Cardiomyocytes devoid of a functional titin protein are elongated and thin when transplanted into a wild-type heart, resembling a DCM phenotype in zebrafish.
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The over-the-top, 20-minute show of heart resembled a telethon.
What makes the discovery especially surprising and puzzling is that the heart resembles a mammal's or bird's but it belonged to an ornithischian, or bird-hipped, dinosaur, one of the two main lineages of these great reptiles.
The results are diversely intriguing: led by resonant bass, "Elephant Decision" is Dead Air's equivalent of "Walk on the Wild Side", while the retro-futurist mode of "Electrical Heart" resembles early Human League fronted by Patti Smith.
Perhaps he even stood once or twice outside his boss's double doors, and his courage was quelled, as the movements outside the double door are quelled, and his heart resembled a squishy cushion, one of those plump leather cushions a manager likes to sit on.
One illustration of a diseased kidney calls to mind the fig Rupert Birkin bites into in DH Lawrence's Women in Love, and which causes him to rhapsodise the female genitals; another carbuncle, prised out from a diseased heart, resembles a huge red effulgent pearl.
The heart resembles that of the amphibian but there is a septum which more completely separates the oxygenated and deoxygenated bloodstreams.
A Slate explainer from 2007 offers a few theories: the heart resembles the leaves of a plant once used as makeshift contraceptive pills; unskilled artists tried, and failed, to replicate the actual appearance of the human heart, which Aristotle said was the source of feeling.
Thus, the M-band composition of mouse heart resembles fast skeletal fibers, while that in human heart is more close to intermediate speed fibers [ 36].
This late addition of cardiomyocytes to the arterial pole of the zebrafish heart resembles the addition of cardiomyocytes from the anterior or second heart field as described in amniotes.
Indeed, the live embryo fluorescence seen in the foregut and heart resembles that seen previously in those domains in fixed embryos for activated phosphorylated Smad1, Smad5 and Smad8 (Wandzioch and Zaret, 2009).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com