Exact(2)
We have earlier shown that the overexpression of wild-type Twinkle in mouse heart promotes recombination junction formation together with an increase in mtDNA copy number [5] (Figure 4D), whereas the Twinkle dup352 364 mutation has been shown to impair helicase activity, resulting in a strong replication stalling phenotype in cultured cells as well as in mice [19].
Some reports have shown that matrix metalloproteinase-2 in heart, which cleaves Col III [ 24], is downregulated during late pregnancy [ 25]; this could suggest that a suppression in matrix metalloproteinase-2 expression in heart promotes Col III expression in extracellular matrix.
Similar(58)
Thus, mending of the heart promoted by CPCs can be an appropriate substrate to explore the proarrhythmic or antiarrhythmic consequences of stem cell based myocardial regeneration.
This can be understood as increasing vagal control of the heart promoting affiliative behavior (i.e., offer acceptance).
AICAR was first developed to block adenosine reuptake in the ischaemic heart, promoting stimulation of adenosine membrane receptors.
FGF23 itself has been shown to mediate off-target direct end-organ toxicity in the heart promoting cardiomyocyte hypertrophy.
Furthermore our results support the notion that long-term p38 MAP-kinase activation may increase post-infarct cardiac remodeling in the diabetic GK rat heart, promoting an increase in fibrosis, cardiomyocyte hypertrophy and an increase in the expression of pro-inflammatory regulators.
The GOP is the only "party pro-life with open hearts" promoting adoption.
"Fundamentally, and at its heart, licensing promotes improvement in standards across the board.
Then the lead of the heart jack promotes West's spade jack as the fourth defensive trick.
Recapitulation of the cellular microenvironment of the heart, which promotes cell contraction, remains a key challenge in cardiac tissue engineering.
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