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Last year, a line in an article on the fate of Barnes & Noble gave my heart pause — and sent me on an all-consuming tear.
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The girl's heart paused.
The man's heart paused.
She placed her hand over her heart, paused, and choked up.
We noticed a similar association of body movement with heart pausing in our en-face imaging observations.
It has been noticed previously that short periods of heart pausing are associated with eating activity and with preparation for crawling in Drosophila larvae [5].
Taking into consideration the natural irregularity of fly heartbeat, we therefore screened Doppler audio recordings for larval heart pausing of longer than 2 seconds.
The Doppler data showed that, compared to control larvae where pausing was a relatively rare occurrence (seen in ∼7% of larvae, n = 27), heart pausing increased to ∼26% (n = 27) in TM23 mutants (Table 1).
We show that a similar phenotype pre-exists at larval stage and demonstrate that this Tropomyosin defect also causes an arrhythmia characterized by increased length and frequency of heart pausing.
For the sword outwears its sheath, And the soul wears out the breast, And the heart must pause to breathe, And love itself have rest.
By Louise Polett and John McCarten The New Yorker, October 8 , 1949P. 19 A six-year-old girl who attended a wedding at St. Thomas watched the proceedings with no evidence of great interest until the minister happened to put his hand over his heart and pause.
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