It is that leap from hypertension to heart outcomes like heart attacks and strokes that critics are unwilling to make.
Indeed, for a range of functional and structural parameters in both the kidney and heart, outcomes were nearly identical for both routes of administration (Fig. S1).
Heart rate, outcome, and catecholamine use did not lead to a significant effect on differences between EV and TTE.
Therefore, targeting patients' expectations might offer a promising opportunity to enhance heart surgery outcome.
Rationale and design of the multicenter, randomized, double-blind, placebo-controlled study to evaluate the Efficacy of Vasopressin antagonism in Heart Failure: Outcome Study with Tolvaptan (EVEREST).
Gheorghiade, M, Konstam, MA, Burnett, JC, Grinfeld, L, Maggioni, AP, Swedberg, K, Udelson, JE, Zannad, F, Cook, T, Ouyang, J, Zimmer, C, Orlandi, C, and Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study With Tolvaptan (EVEREST) Investigators,.
The Efficacy of Vasopressin antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) trial is evaluating mortality, morbidity, and patient-assessed global clinical status in patients treated with tolvaptan compared with standard care.
Survival rate and longitudinal models were used to estimate temporal changes in postdischarge all-cause mortality risk in 3,993 HHF patients discharged alive in the Efficacy of Vasopressin Antagonism in Heart Failure Outcome Study with Tolvaptan (EVEREST) trial.
In this post hoc analysis of the Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study with Tolvaptan trial, we analyzed serum osmolality measured at discharge in 3,744 patients hospitalized for HF and reduced ejection fraction (EF ≤40%).
METHODS: This post-hoc analysis of the EVEREST (Efficacy of Vasopressin Antagonism in Heart Failure: Outcome Study With Tolvaptan) trial examined 1,947 patients with HHF and EF ≤40% not in atrial fibrillation/flutter or pacemaker dependent.
