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To determine whether trientine treatment could improve in vivo outcome, we measured cardiac function in groups of trientine-treated diabetic (TETA-DIA), non-drug-treated diabetic (DIA) and sham-treated control (SHAM) rats, by using in vivo high-field cardiac magnetic-resonance imaging (cMRI) and an ex vivo isolated-perfused working heart method.
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At the heart of kernel methods, the "kernel-trick" makes use of kernel functions to remap input data into a high dimensional feature space where a variety of methods can be used to efficiently analyze the data (e.g.: find a margin-maximizing separating hyperplane, in the case of SVM).
The quantitative assay was applied to test 132 oysters, and results were compared with the heart imprint method.
At its heart, this method overcomes the incidental parameter problem by conditioning on each respondent's observed value of the nuisance parameter's sufficient statistic, i.e. the score r v, when estimating the item parameters.
Basic heart volumetric method proposed by Baan et al. [4, 5, 12] is based on obtaining SV and cardiac output by the means of an intra-cardiac measurement of the electrical impedance of the time-varying conductance of blood contained within the left LV cavity.
Blood was collected by direct heart puncture method.
Using an external heart pacing method (Wessells & Bodmer, 2004), we tested cardiac stress resistance.
For further details of the Langendorff heart perfusion method, see Supplementary material online, S1.
Physical fitness was estimated once at baseline using the submaximal cycle ergometer heart rate method [ 25].
After 14 days, the animals were sacrificed under mild ether anesthesia, and the blood was collected by direct heart puncture method.
However, many questions still remain to be answered regarding the optimal approach to take for evaluating the significance of EAT, including its pathophysiological roles in ischemic heart disease, method for quantification, and clinical relevance on ischemic heart disease.
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