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In the HF-C and EN-C groups, liver, spleen, kidney, and heart masses were all normalized at week 19.
Table 1 reports the liver, spleen, kidney, and heart masses for each diet group at weeks 0, 7, and 19.
After 7 weeks, the high fat plus liquid Ensure diet resulted in increased liver, spleen, and heart masses versus chow or high fat diet alone (P<0.05).
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The heart mass index, left ventricular mass index and hydroxyproline content of both groups were compared.
By then, the animals' heart mass had soared 63%, a key sign of heart weakness.
Echocardiograms showed that in the treated animals, heart mass gradually declined.
Contraindications to the insertion of PAC include tricuspid or pulmonary valve endocarditis/mechanical valve and right heart mass or thrombus.
MRI results after 6 months showed reductions in scar mass, increases in viable heart mass and contractility in the treated group [69].
Heart mass was significantly affected by genotype (Figure 3F, p = 0.0012).
MYBPC3 is a thick filament associated protein in the cardiac sarcomere which contributes 2% of the total heart mass.
Further studies are needed to determine how the observed alterations in heart mass and function evolve over time.
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