Echocardiograms showed that in the treated animals, heart mass gradually declined.
By then, the animals' heart mass had soared 63%, a key sign of heart weakness.
The heart mass index, left ventricular mass index and hydroxyproline content of both groups were compared.
Contraindications to the insertion of PAC include tricuspid or pulmonary valve endocarditis/mechanical valve and right heart mass or thrombus.
MRI results after 6 months showed reductions in scar mass, increases in viable heart mass and contractility in the treated group [69].
In response to pressure overload stress (an experimental model of hypertension), DN-Lats2 Tg mice were protected against cardiomyocyte apoptosis and showed an enhanced hypertrophic response, i.e., individual cardiomyocyte enlargement leading to greater overall heart mass [135].
Our results showed that the heart mass index, left ventricular mass index and hydroxyproline content in the left ventricles of the aged mice were increased significantly compared with the adult mice, indicating that left ventricular remodeling occurs with aging.
Heart mass was significantly affected by genotype (Figure 3F, p = 0.0012).
MYBPC3 is a thick filament associated protein in the cardiac sarcomere which contributes 2% of the total heart mass.
Further studies are needed to determine how the observed alterations in heart mass and function evolve over time.
Heart mass was decreased in Akt1ko mice with treatment however not in WT or Akt2ko mice (Figure 3F, p<0.05).
