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Moreover, when ECG traces were obtained from immunized mice, the heart functional alterations observed at 10 days continued at 80 and 150 days after the third immunization, showing an association with the levels of antibodies.
The immunization of BALB/c mice with R13 synthetic peptide coupled to a carrier protein (OVA) induces specific (anti-R13) and autoreactive (anti-H13 and anti-heart) antibodies as well as heart functional alterations.
Also, right heart functional abnormalities exist in patients with septic shock.
Finally, the heart index (HI), reflecting heart functional capacity, was calculated as heart weight (g)/total weight (g) × 100.
The heart index reflects heart functional capacity, i.e. aerobic performance, organ aerobic activity, and the animal's ability to engage in physical activity.
Work with the fly heart illustrates the autonomous role where increased dFOXO specifically within cardiac tissue is sufficient to slow heart functional aging (Wessells et al., 2004).
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Huang, W., Zhang, R. & Xu, X. Myofibrillogenesis in the developing zebrafish heart: a functional study of tnnt2.
Sweden briefly found itself at the heart of functional modernism and it suited Greene's purposes well.
However, documentation of New York Heart Association functional class was rare; limiting quantifiable evaluation of response to therapy throughout programme enrolment.
Forty-seven patients (12 women; mean age 56.5 ± 9 years) with angiographically proved IDC, in New York Heart Association functional classes II to III, and who had left ventricular ejection fraction 30.6 ± 9.5%, and 20 healthy controls were studied with planar MIBG.
One-half of the patients were in New York Heart Association NHYAA) functional class III or IV pre-implantation.
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