Exact(2)
TCL1B enhances the phosphorylation and activation of AKT1 (V-akt murine thymoma viral oncogene homolog 1) and AKT2 (V-akt murine thymoma viral oncogene homolog 2), two proteins involved in heart function and heart development.
The 2 phases comprising inflammatory Ly-6Chigh monocyte recruitment and reparative Ly-6Clow macrophage differentiation are essential to post-MI recovery; their perturbation (ie, in the context of comorbidities) leads to impaired heart function and heart failure.
Similar(58)
The angiogram showed significant blockage in a number of coronary arteries, normal heart function and no heart attack.
He cited as an example the Swan-Ganz catheter, a device threaded into the heart to monitor heart function and blood flow.
Atrial fibrillation may be associated with underlying cardiomyopathy that has resulted in poor heart function and enlargement of the heart or it may occur with when the heart is structurally and functionally within normal range.
Heart muscle damaged during MI is replaced by a collagenous scar over a period of several weeks, and the mechanical properties of that scar tissue are a key determinant of serious post-MI complications such as infarct rupture, depression of heart function, and progression to heart failure.
However, researchers haven't had the tools to study how disease-induced structural changes in the heart might be affecting heart function and blood flow.
Groups of animals (>10/group) allowed the following indexes to be analyzed: survival of animals, invasive blood pressure (BP), lactate rate, heart function and cytokine profile using plasma, organs (heart, kidney, lung, liver and brain) and RT-PCR 18 hours after surgery.
This suggests that the old mutants had decreased heart function and may have experienced heart failure.
Right heart function and remodeling were assessed by right heart catheterization, magnetic resonance imaging (MRI), and histomorphometric methods.
The β-adrenergic signaling pathway plays a key role in the regulation of normal heart function and the development of heart failure [ 1- 5].
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