Sentence examples for heart fields from inspiring English sources

To track the earliest Mesp1-expressing cells during ESC differentiation, Bondue et al. generated Mesp1-GFP reporter ESCs and showed that these early Mesp1-expressing cells were enriched for MCPs of both heart fields, which gave rise upon differentiation to all cardiovascular cell lineages both in vitro and in vivo.

These results indicated Mesp1 at least marked the precursors of multipotent cardiovascular progenitors (MCPs) of both heart fields and was required for these precursor cells to depart from the primitive streak and to generate a single heart tube (Saga et al., 2000).

During stem cell differentiation, Brachyury T expression marks the precardiac mesodermal cells; Mesp1-expressing cells represent early multipotent cardiovascular progenitors; Nkx2-5 and Islet1 reporter genes are used for isolating cardiovascular progenitors of the first (Nkx2-5) and the second heart fields (Nkx2-5 and Islet1).

Nkx2.7 and Nkx2.5 express in zebrafish heart fields of lateral plate mesoderm.

The primary and secondary heart fields of the embryonic disc give rise to the intracardiac structures of the heart under the influence of adjacent tissues [8].

Consequently we anticipated that our transcriptional analyses could identify transcripts present in both heart fields, as well as those exclusively present in one heart field.

The left ventricle cardiac progenitors are mainly derived from the primary heart field, and the right ventricle cardiomyocytes are from the secondary heart field [8].

Cardiac morphogenesis and maturation require the deployment of multiple cell lineages that are derived from the primary heart field, secondary heart field, and neural crest cells [4 6].

Interfering with cardiac progenitor recruitment from the secondary heart field resulted in a small right ventricle.

Subsequently, the primary heart tube is elongated by recruiting cells that are generated from the second heart field.

Thus, it was impossible to affect cardiac progenitor recruitment from the secondary heart field because MLC2a was expressed in differentiated cardiomyocytes instead of in cardiac progenitors of the secondary heart field.