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In 3 patients, the mean heart dose was more than 2 Gy (Fig. 1).
In the left BC patients, the mean heart dose was higher with HTgF versus STgF (2.6 vs. 1.4 Gy; p = 0.02).
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First, the clinical target volume (CTV) to planning target volume (PTV) margin needed to account for respiratory motion means that the lung and heart dose is higher than would occur in the absence of such motion.
It has been shown that decreasing of the mean heart dose is relevant [ 6].
Respiratory control techniques to reduce heart dose are highly recommended for left sided breast cancer patients.
The current average mean heart dose is likely to be around 2 7 Gy for left-sided (Taylor et al, 2008; Jagsi et al, 2010; Schubert et al, 2011) and around 1.5 Gy for right-sided breast cancer radiotherapy (Taylor et al, 2008).
Average heart mean dose was 20 Gy (range 13-28).Acutoxicityity during radiation included dysphagia (5/9), fatigue (4/9), nausea and weight loss (1/9) and skin desquamation (9/9).
She was hospitalized many times due to heart failure, and diuretic agent dose was gradually increased.
For heart disease, the estimated threshold dose was 0 Gy, with an upper 95% confidence limit of about 0.5 Gy.
Apart from the mean heart dose, there are data suggesting that the dose to the LAD coronary artery is most at risk for developing atherosclerosis after left-sided breast-conserving radiotherapy due to its anatomical position in relation to the breast [ 7].
Partial Cox regression analysis showed that controlling for ischemic heart disease and heart failure, ESA dose is a risk factor for CVE.
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