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Additional studies are necessary to understand if MFBs are not only proarrhythmogenic in heart failure but also during heart development and aging; these are frequently subjected to other pathological "MFB-triggering" situations (diabetes, autoimmune disorder, and metabolic diseases).
Similar(59)
The overall pattern of changes with aging and lifestyle in seal skeletal muscle shows similarity to heart development and involves profound changes in cytoskeleton structure and energy metabolism.
Thus, the Hippo pathway is indispensable for regulating embryonic heart development and maintaining basal heart homeostasis.
"I looked at what neuregulin was doing in heart development and heart disease," Ford explains.
Mef2c is important for heart development and cardiomyocyte differentiation.
Apoptosis is a highly regulated process during embryonic and postnatal heart development and critical for heart development.
These genes mainly belong to developmental processes such as heart development and blood vessel development.
CNCC play multiple roles during heart development and are particularly essential for OFT development.
The homeobox transcription factors NKX2-5 and MEIS1 are essential for vertebrate heart development and normal physiology of the adult heart.
In zebrafish, ATOH8 is required during heart development and it genetically interacts with heart transcriptional regulators GATA4 and FOG1.
This gene is activated at the heart chambers during heart development and is expressed over adult life [ 18].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com