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Since cardiac tissue has a limited regenerative capacity, any insults against the heart cause an irreversible myocardial damage dependent upon nature and magnitude of the insult, consequently inducing acute and/or chronic cardiac failure.
It seems highly unlikely that abnormalities in cell migration into or within the heart cause the defects, as Scrib f/f;Wnt1-Cre and Scrib f/f Isl1-Cre, in which Scrib is deleted in migratory NCC and second heart f/f Isl1-Cre respectinely, are phenotypically normal.
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Most disease-causing LMNA mutations affect the heart, causing a dilated cardiomyopathy, with or without skeletal muscle involvement.
The heart caused the most problems.
Indigestion generates stomach gas which presses against the heart causing pain there.
The virus that had made her ill had probably attacked her heart, causing viral myocarditis.
She has chronic venous insufficiency, in which the leg veins struggle to return blood to the heart, causing terrible pain.
In later stages of thyroid deficiency, fluid may accumulate around the heart, causing a condition known as pericardial effusion.
The most common of the three illnesses, ischemic heart disease, restricts blood flow to the heart, causing irregular heartbeats and deterioration of the heart muscle.
East would have won and led a heart, causing the declarer to discover that his three heart stoppers were not enough.
Without antibiotics, bacteria introduced into the body in those procedures can travel through the blood to the heart, causing potentially deadly infections.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com