Madonna recorded "Open Your Heart", altered the lyrics thus earning a co-writing credit, and along with Patrick Leonard added a bassline underneath the song which turned it into a rock-dance track rather than the original rock 'n roll genre.
Investigators should be aware, however, that QT prolongation can be the result of non-hERG channel-mediated mechanisms, indirect changes in autonomic nerve tone into the heart, altered channel density or properties, heart rate over-correction, and the emergence of metabolites.
However, many existing gene therapy approaches (such as some AONs used for exon skipping and AAV serotype-9-mediated systemic gene transfer in newborn dogs) cannot efficiently reach the heart (Alter et al., 2006; Hakim et al., 2014; Yokota et al., 2009; Yue et al., 2008).
Whether the β-1 agonist dobutamine, which is frequently administered to patients with heart failure, alters their chemoreflex sensitivity is not known.
Cardiac autonomic function is also altered by PM exposure, suggesting that central input to the heart is altered (Chen and Hwang 2005).
That ritual is reserved principally for men with the muscles to hit a baseball very far, not people with a mind or a heart to alter the world.
Altman's one-day stint with the Razorbacks — after what he deemed a late change of heart — ultimately altered the direction of three programs.
Isoproterenol administration showed changes in ECG pattern, including ST-segment elevation (diagnostic of myocardial infarction) increase in the serum levels of cardiac injury markers (creatine kinase-MB, lactate dehydrogenase, aspartate transaminase and alanine transaminase), decreased antioxidant defense system in the heart and altered lipid profile in the serum and heart.
Glucose transporter expression in the heart is altered in various pathological states.
Setting of new marker points in a specific heart phase altered the volume cast of the whole heart automatically.
