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It combines biomechanical properties that are held accountable for fast bone healing: (1) high primary fixation stability; (2) a compliant bone-implant construct which allows residual micromotion within the osteotomy gap to promote a "callus massage".
Healing #1, acrylic and charcoal on paper, 82 x42".
Much of the attention has focused on increased rate of infections and poor wound healing (1, 22).
The follow up schedule after the surgery was daily from day 1 till epithelial healing, 1 week, 1 month, 3 months, 6 months, 1 year and yearly thereafter.
Structural and functional changes in small fibers precede large-fiber pathological changes and have been implicated in foot ulceration and delayed wound healing (1– 3).
It is recommended as a second-line therapy in steroid-dependent or -refractory disease, although first-line treatment may improve chances of intestinal mucosal healing (1).
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The "drill hole" model proved a good system for evaluating bone healing [ 1, 19, 20].
Beneficial effects have been cited as decreased drainage, decreased incidence of dehiscence, decreased infection rates and improved wound healing [ 1, 19, 20].
Using well established mouse models of skin and mucosal wound healing [ 1, 2, 7] and advanced microarray technology, similarly expressed as well as significantly differentially expressed genes in skin and mucosal wounds were successfully identified.
These pathologies have in common a loss of corneal sensitivity leading to impaired healing [1].
The osseointegration process is quite similar to the primary bone healing [1].
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