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Neurostimulation is of increasing interest in headache therapy.
A recent study reports non-adherence to medical prophylaxis in headache therapy in up to 35% of the patients.
Only 30% of their patients were satisfied with their headache therapy, whereas 63% were dissatisfied, and 7% felt neutral [14].
Methysergide and injectable dihydroergotramine are rather effective in cluster headache therapy but currently unavailiable in most countries.
The absence of clinical guidelines specifically designed for headache therapy in pediatric emergency may interfere also on this habit and on the choice of medications [13].
MOH is not simply a highly frequent migraine or TTH and, consequently, efforts to treat MOH by applying the basic principles of primary headache therapy are often unsuccessful.
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Until the mid 1990s, combination analgesics with codeine or caffeine, or ergots combined with codeine were the most common headache therapies in many European countries [30, 38, 40].
The education CD-ROM also covered health habits (e.g., sleep, diet, physical activity), but no "active" psychological headache therapies (e.g., relaxation, cognitive restructuring) were contained in this program.
It would be intriguing to investigate, first, whether early recognition and a correct and prompt anti-headache therapy can prevent this cognitive different profile and, second, whether the cognitive profile associated with headache is reversible at any time during the course of the disease.
As the opioid was not effective in the treatment of the patient's headache, gabapentin therapy was reestablished.
Placebo control, which is particularly essential for (headache) pain therapy due to the variable placebo effect [22].
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