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However, causal relation of headache aggravation after sumatriptan spray was not ascertained in that study.
Model 1 included sociodemographic variables (age, sex, size of residential area, and education level) and headache aggravation by movement.
Headache aggravation by movement and depression were significant indicators of the presence of RLS among individuals with TTH.
Univariable and multivariable analyses indicated that headache aggravation by movement is an independent predictor of RLS among participants with TTH (Table 3).
One of the novel and interesting results of this study was that significantly more TTH sufferers reported headaches limited to the menstrual period, even though more migraineurs in general reported headache aggravation during menstruation.
Multivariable analyses revealed that headache aggravation by movement (odds ratio [OR] = 2.4, 95% confidence interval [CI] = 1.1 5.2) and depression (OR = 3.5, 95% CI = 1.1 11.4) were significant indicators of RLS among individuals with TTH.
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Further studies are essential to know whether headache aggravations or appearance of headache in MV patients are attack-related events, patient-related effects or drug-related events.
CO2-induced headache attacks or aggravation were less intense than headaches triggered by histamine and adrenaline [37].
The risk of other common adverse events, such as rash, dizziness, headache and seizure aggravation, were not significantly different (figure 5).
The insomnia and the bruxism are factors of chronification and aggravation of headache.We found the significant correlation between headache and emotional disorders.In the M with CM there are externalizing disorders (10%, 66% of CTT show both internalizing and externalizing disorders, and 18% have externalizing disorders.
Transient aggravation of headache by triptans has been reported in few studies [8].
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