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Posterior segment examination (Fig. 1) demonstrated trace vitreous cell, grade II optic nerve head edema, foveal granularity, and a circinate distribution of RPE white dots.
In contrast, unvaccinated control animals rapidly developed typical symptoms of severe avian influenza (head edema, ruffled feathers, diarrhea, depression) and died at day 3 post-infection.
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As illustrated in Fig 3A, MO1 morphants clearly showed small eyes, a small head, and brain edema at 1 and 2 dpf.
In contrast, the puf-A siRNA (without nanos 3' UTR) had the similar phenotypes as MO morphants with small eyes, small head, and brain edema in addition to abnormal PGC migration and reduction in PGC number (Fig. 4B).
Alterations in the distribution of water and cerebrospinal fluid in the brain are a common occurrence in multiple neuropathological conditions, including brain edema, brain tumors, stroke, hyponatremia, head injuries and hydrocephalus.
Head CT revealed remaining brain edema with mild midline shift despite removal of the main lesion (Fig. 2).
After admission, they required continuous diazepam or barbiturate infusion for seizure or brain edema with the head of the bed elevated 30°.
Despite the removal of the main lesion, brain edema was still observed on head CT.
Significant brain edema was confirmed in the head CT after the surgery although the right temporooccipital tumor had been removed Fig. 3 Chest CT after craniotomy.
In our previous experimental study we evaluated the effects of magnesium on brain edema formation and BBB breakdown after closed-head trauma in rats [ 5].
The relationship between vasopressin levels and brain edema development has also been demonstrated in a clinical study of head injured patients [ 30].
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