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He has doomed himself politically, to Albany or death.
Realising that he has doomed them to a hideous fate, Edward allows the humans to shelter in his car until the authorities have passed on.
"We expected him to be a champion for immigrants, but by his failure to take leadership, he has doomed thousands," Reshma Shamasunder, executive director of the California Immigrant Policy Center, said of Brown.
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Rejected in attempts at romance, he had doomed affairs with demimondaines; for a time, he lived with a Dutch prostitute who had two children, gaining a taste of domestic happiness that haunted him ever after.
Mr. Bartman's critics claimed that he had doomed the Cubs' chances, and his defenders -- seemingly a growing bunch -- claimed that Cubs fans were trying to blame the team's athletic failings on an innocent spectator.
After losing the House, Trump proclaimed victory while mocking the more temperate GOP incumbents he had doomed to defeat.
He is convinced that his failure has doomed his unborn child to a life of trouble.
Many believe it has doomed itself.
The Enron scandal has doomed his plan.
Money has doomed more designers than it has made.
It is that familiarity that has doomed them.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com