"We used to write revues together," says Frayn. "He was already developing his sketch as a clergyman which he developed further in Beyond The Fringe.
In Creation: An Appeal to Save Life on Earth (2006), he developed further the evolutionarily informed humanism he had earlier explored in On Human Nature.
He developed further interests in protein and, together with biochemist Alfred Mirsky, Pauling published a paper in 1936 on general protein structure.
Following his work on insulin he developed further methods for studying proteins, particularly the active centres of some enzymes, and in about 1960 took on the challenge of determining the order of bases in DNA, known as DNA sequencing.
And in the increasingly ornate second half of the set, he introduces comparatively sudden, dramatic change in place of slow evolution: an approach that he developed further in "Koyaanisqatsi" and other scores of the early 1980s, and that has become his standard operating procedure.
His poems of The Man in the Black Coat Turns (1981) explore themes of male grief and the father-son connection that he developed further in Iron John and also The Maiden King: The Reunion of Masculine and Feminine (1999), written with Marion Woodman.
Over the subsequent weeks, and without a clear precipitating factor, he developed further medial pain.
Until the science develops further, that question is unanswerable, he said.
