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Figure 2 Hazard of relapse for postmenopausal patients treated at Istituto Nazionale Tumori in Milan, Italy.
Figure 1 Hazard of relapse for premenopausal patients treated at Istituto Nazionale Tumori in Milan, Italy.
Similarly, the time to relapse was different between countries and a difference of 1 unit in the EQ-5D overall health status score (the total EQ-5D range was −0.59 to 1) was associated with a 54% reduction in the hazard of relapse.
Those who engage in such practice at least three days/week approximately halve hazard of relapse.
Formal home practice is negatively associated with hazard of relapse to depression.
There would be a significant association between average daily duration of formal home practice and hazard of relapse to depression.
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This was shown by a suggestive, though not statistically significant trend in multivariate analysis, towards reduced hazards of relapse in the presence of combined HLA-DPB1-DPA1 allelic mismatches, compared to HLA-DPB1 mismatches but –DPA1 matches.
The independent influence of several factors on the risk of nonresponse, relapse or nonsurvival was assessed by logistic regression, while that on the hazards of relapse or failure of survival by Cox's proportional-hazards model (Collet, 1999; Tangent and Koch, 1999).
Cox univariate regression analysis revealed that hTERT mRNA-positive patients had a high and statistically significant risk of relapse (hazard ratio (HR) of 2.24 and P=0.038).
Natalizumab patients had a significantly lower risk of relapse (hazard ratio [HR] 0.695; 95 % confidence interval [CI] 0.59 0.82) during the 12-month post-period; the adjusted Cox model yielded the same result (HR 0.693; 95 % CI 0.59 0.82) (Table 2; Fig. 2).
In a backward model, a SCA genomic profile was found to have a higher risk of relapse (hazard ratio: 5.24, CI 2.4 11.4, P<0.0001), whereas a lower risk of relapse was observed for treatment group INES99.3 (hazard ratio: 0.32, CI 0.094 1.11, P=0.076).
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