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They were annotated automatically (with manual validation) by nicknames of the organisms having overrepresented or underrepresented numbers of domains (Supplementary Table 6S).
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The polls' samples might have overrepresented well educated voters.
For adipogenesis the promoters of 26 genes had overrepresented TFBS for 20 transcription factors and for osteoblastogenesis promoters of 39 genes had overrepresented TFBS for 11 transcription factors.
We found that 237 GO terms had overrepresented numbers of genes in ≥1 phase cluster.
Human gene-associated repeats – particularly coding region repeats – are known to have overrepresented GO terms indicative of regulatory function [ 12].
Four out of five UCR clusters that have overrepresented homeobox domains of nearby genes come from human, fruit fly, and sea urchin.
The results showed that R. microplus ticks fed on cattle have overrepresented tick proteins involved in blood digestion and reproduction when compared to ticks fed on WTD, while host proteins were differentially represented in ticks fed on cattle or WTD.
In summary, the results of the proteomics analysis showed that R. microplus ticks fed on cattle have overrepresented proteins involved in feeding (blood digestion) and reproduction when compared to ticks fed on WTD.
The bias is related to case definition (which was not very specific), the selection of the controls (people who agreed to act as controls were well enough to answer our questions, so the control group may have overrepresented people in good health), and information bias (the case or control status was known by the investigator and the controls).
The practices of some physicians may have been overrepresented relative to the target population, and bias may have been introduced via errors in laboratory measurements and variations in FN risk assessments among physicians.
One potential limitation of the study was the possibility of selection bias, as optometrists with a specific interest in diabetes may have been more likely to accept the invitation to participate and hence may have been overrepresented in the study.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com