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However, the ability to predict polysaccharide substrates and catalytic potentials of these enzymes was impeded by the lack of specific annotations in the databases because very few of the highest scoring BLASTP alignments have corresponding KEGG E.C. annotations.
An alternative involves a search and score approach: choose three residues from each sample that have corresponding amino-acid labels and share some geometric feature, then score the alignment produced from superimposing these residue triplets.
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As expected, the fiber alignment of the gradient meshes induced a corresponding alignment of adherent cells in static culture.
Alignments of the top 20 hits are extracted from the corresponding alignment dataset.
The ROI chosen for each test case, and the corresponding alignment search space are presented first.
It returns the corresponding alignment.
The ten biggest Pfam entries containing 9,000-10,000 sequences, which have a corresponding HOMSTRAD alignment are used here.
The HOMSTRAD/Pfam benchmark comprises of Pfam entries containing up to 10,000 sequences, which had a corresponding structural alignment for two or more of the sequences in HOMSTRAD.
Each Pfam entry containing up to 10,000 sequences and which had a corresponding structural alignment for two or more of the sequences in HOMSTRAD [ 21] was retrieved from the database.
Hence, each sequence in a multiple alignment must have a corresponding sequence in another alignment (see Figure 1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com