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Moreover, we found that CHD4 directly bound PAR chains, which concurs with CHD4 having a leading function in recruiting other NuRD subunits to DNA-damage sites.
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Collectively, these findings suggested that CHD4 is recruited to DNA-damage sites as part of the NuRD complex and that CHD4 has a leading function in NuRD recruitment.
Although p53 status has a leading function in determining the efficacy of apoptotic signalling, tumour cells including EOC can evade apoptosis using multiple mechanisms (Johnstone et al, 2002; Kaufmann and Vaux, 2003; Quintieri et al, 2007).
We ran a hierarchical regression, controlling for gender, tenure, fulltime versus part-time employment (dummy-coded) and whether or not the respondent has a leading function (dummy coded).
Her daughter had a leading role.
He has a leading 14 horses entered.
Every Whirlpool employee is either leading self, leading others, leading function, or leading enterprise.
Have a cheer leading squad and practice cheer leading everyday.
This accords with the function of the wings as airfoils having a stiff leading edge and a flexible trailing edge.
Therefore, they may be responsible for altering the conformation and subsequent change in activities of key proteins having reproductive function leading to infertility.
In theory, because the commissioner – Britain's leading police officer – has a national function in areas such as counterterrorism and is answerable to the home secretary as well as the mayor and the Metropolitan Police Authority, he could have fought the move.
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