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Cancer cells have upregulated glucose transporter expression, and they tend to reprogram their metabolic pathway to "aerobic glycolysis".
Ovarian cancer cells that have metastasized to adjacent adipose tissues have upregulated expression of genes encoding fatty acid transport proteins such as CD36 and FABP4, together with other molecules including CD31, CD34, VEGFR1, and VEGFR2 (Gusky et al., 2016).
We detected a correlation of 0.62 between phosphorylation state of S6K1 and total eIF2Bε abundance, and a correlation of 0.58 between phosphorylation state of S6K1 and total eIF2α abundance, suggesting that mTORC1 activation may have upregulated eIF2Bε and eIF2α expression.
Increased CD95 on monocytes from children with autism may represent an activated subset of monocytes that have upregulated the surface expression of this apoptosis marker.
Perhaps consistent with decreased ability to respond to oxidative stress, AA astrocytes have upregulated transcription of an array of cytoprotective genes responsible for stabilizing the cytoskeleton.
It is possible that these cells derive from CD8+ T cells that have upregulated the CD4 coreceptor generating DP T cells endowed with antigen non-specific effector functions.
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Sixty-eight per cent of samples with upregulated miR-221 (cutoff: 48) also had upregulated miR-18a (cutoff: 446).
HL leaves had upregulated their light utilization through higher photochemical quantum yield (ΔF/Fm′) and greater electron transport rate.
Glucose-6-phosphatase (G6Pase) is an essential metabolic enzyme that has upregulated activity in Type II diabetes.
These cells had upregulated markers of negative selection and were apoptotic.
Interestingly, the liver of Hfe−/− mice has upregulated expression of APPs such as serum amyloids, lipocalins and orosomucoids.
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