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These results imply that ADAR1 and ADAR2 have biological functions as RNA-binding proteins that extend beyond editing per se and that even genomically encoded ADARs that are catalytically inactive may have such functions.
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Beside the destruction of bone tissue by osteoclasts or osteoclast-like cells, we could confirm that FSCs from RA patients inoculated in vivo showed aggressive behavior, invading cartilage as reported previously [ 31- 33], although we have not yet confirmed that pure RA-NLC lines have such function.
To meet the requirements of reactor analysis, RMC now has such functions as criticality calculation, fixed-source calculation, burnup calculation and kinetics simulations.
Starting from a known event (SafA in Escherichia coli) we consider further proteins, which could have such connector functions and examine their potential to change TCS function.
They have such competing functions.
lpPhox2 in squid may have such developmental functions.
Why do DDR proteins bind and have such important functions at telomeres rather than being excluded from the ends of chromosomes?
To understand how kinesins with structurally similar motor domains can have such dissimilar functions, we elucidated the ATP turnover cycle of the kinesin-13, MCAK.
In support of this concept, a number of neurotransmitters have been described in the last decade to have such a function, with the catecholaminergic system being best characterized.
However, several lines of evidence argue that Elba does in fact have such a function for the endogenous Fab-7 boundary.
Deacon's idea of relaxed selection, he says, "allows mutations to modify certain genes and inactivate others so they don't have such a specific function".
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com