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Genome-wide association studies (GWAS) have successfully discovered a number of disease-associated genetic variants in the past decade, providing an unprecedented opportunity for deciphering genetic basis of human inherited diseases.
Millions of individuals have successfully discovered and utilized strategies and tools to initiate and sustain long-term recovery.
We have successfully discovered a large number of SNP markers in A. auriculiformis x A. mangium hybrids using next generation transcriptome sequencing.
So although GWAS have successfully discovered SNPs influential for (or which tag variants which influence) a large variety of phenotypes, with standard sample sizes, they will struggle to detect SNPs of moderate or weak effect.
In summary, several 2D and 3D virtual screening approaches have successfully discovered structurally diverse natural product PPARγ activators, thereby indicating natural products as a rich source for novel PPARγ agonists.
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In the past, our laboratory has performed screening for multiple TCM components and has successfully discovered novel lead compounds, such as anti-viral, anti-inflammation, anti-cancer, stroke prevention compounds, and hypnotic medications [6] [17].
The other important feature of the MAB is that subjects were forced to continue exploring alternative solutions, once they had successfully discovered and consistently used one particular solution, by blocking the one in use.
Versatile synthetic methods via double Suzuki coupling to explore SAR have been established and potent inhibitors against angiogenetic targets, VEGFR2, Tie-2, and EphB4, have been successfully discovered.
In the past decade, the main pathway of glucosinolate (GS) biosynthesis has been well understood in A. thaliana and B. rapa, and many critical genes have been successfully discovered and functionally characterized [ 34, 35].
Some oil and gas reservoirs have been successfully discovered in the central western China using this method.
The timing characteristics that have been successfully discovered are in relation to the relay trip assertion activity, impedance element activation, fault characteristics, circuit breaker operation and its overall decision system approximation.
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