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Ms. Bachmann would have substantial obstacles to overcome.
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We have substantial debt.
Mr. Putin, you have substantial achievements.
So companies now have substantial foreign shareholders.
All four have substantial land holdings.
Italy and Germany have substantial natural gas vehicle fleets.
"But it could have substantial persuasive force".
We have substantial positions in Yahoo!
He accepts many people have "substantial reservations ".
DO YOU HAVE substantial investment income?
However, clinical trials have demonstrated substantial obstacles to their use, such as immunogenicity and inflammatory potential[26].
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