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Mark Lever, the charity's chief executive, said: "We have substantial concerns about the introduction of a face-to-face assessment for the new benefit.
A number of studies have found that many pregnant women are still unaware that they should be vaccinated or have substantial concerns about adverse effects of the vaccine on them and/or their foetus [ 51- 53].
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Third, the board has substantial concerns about the underfunded status of United's pension plan.
However, each reviewer has substantial concerns that would need to be addressed before publication of the paper could be considered.
Studies reported that a proportion of clinicians had substantial concerns about promoting vaccination, particularly for younger age groups [ 17].
However, several of us had substantial concerns, and while in the end we decided to allow for revision, the following points should be addressed: 1) Stimulation by KCl is highly non-physiological and thus the intermediate structures described here may only become apparent at extreme stimulation conditions.
A joint select committee of MPs also had substantial concerned when it reported earlier this year.
As you will see, while the reviewers found the work potentially interesting, all three have substantial and overlapping concerns with the manuscript, including the design, analysis and interpretation of the study, and the advances that it makes over existing work.
"We all have substantial and increasing concern at the potential of the English law of defamation to affect our work unjustly and oppressively," a consortium of foreign newspapers, publishers and human rights organizations, including The New York Times, said in a statement to the committee.
Union employees have substantial power in addressing workplace-environment concerns, which can be an issue for a chef inclined to shout at his employees.
Privacy advocates say that collecting license plate numbers on public streets raises concerns — and they have substantial questions over where the numbers might end up once they are collected.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com